Table 4.
Allele frequency of (CA)n polymorphism in the LIMD1 gene in head and neck cancer cases and control
| Allele | No of (CA)n repeats | Case | Control | P# | ||
|---|---|---|---|---|---|---|
| No. of alleles | % | No. of alleles | % | |||
| (CA)9 | 9 | 7 | 2.38 | 11 | 2.94 | 0.6571 |
| (CA)13 | 13 | 4 | 1.36 | 35 | 9.36 | 0.00012 |
| (CA)17 | 17 | 23 | 7.82 | 46 | 12.29 | 0.0592 |
| (CA)19 | 19 | 97 | 32.99 | 169 | 45.19 | 0.00139 |
| (CA)20 | 20 | 66 | 22.45 | 36 | 9.63 | 0.000005 |
| (CA)21 | 21 | 21 | 7.14 | 15 | 4.01 | 0.075134 |
| (CA)24 | 24 | 30 | 10.2 | 23 | 6.15 | 0.05427 |
| (CA)26 | 26 | 2 | 0.68 | 15 | 4.01 | 0.0067 |
| (CA)27 | 27 | 19 | 6.46 | 13 | 3.48 | 0.0728 |
| (CA)30 | 30 | 10 | 3.4 | 6 | 1.6 | 0.1316 |
| (CA)32 | 32 | 14 | 4.76 | 5 | 1.34 | 0.0082 |
| (CA)38 | 38 | 1 | 0.34 | 0 | 0 | 0.259 |
| Total no. of alleles | 294 | 100 | 374 | 100 | ||
| χ2 = 29.175, df = 11, P = 0.0021 | ||||||
| Genotype | Case | % | Control | % | P# | |
| (CA)17/(CA)17 | 6 | 9.23 | 11 | 15.94 | 0.2434 | |
| (CA)19/(CA)19 | 33 | 50.76 | 56 | 81.16 | 0.0002 | |
| (CA)20/(CA)20 | 19 | 29.23 | 2 | 2.89 | 0.00003 | |
| (CA)21/(CA)21 | 5 | 7.69 | 0 | 0 | 0.0247 | |
| (CA)24/(CA)24 | 1 | 1.54 | 0 | 0 | 0.4851 | |
| (CA)32/(CA)32 | 1 | 1.54 | 0 | 0 | 0.4851 | |
# From Fisher's exact test.
OR, Odds ratio
CI, Confidence interval