Figure 4.

Effect of iloprost on infiltration of inflammatory cells into the airways after bleomycin (Bleo) injection. The mice were injected with 2 mg/kg of Bleo (no iloprost) or bleo+iloprost, BAL fluid was collected at days 3, 7, and 14 later. The number of inflammatory cells and lymphocytes accumulated in airways was significantly higher in the mice treated with Bleo (no iloprost) than those treated with Bleo+iloprost (A and B), and there was no significant difference in the number of macrophages and neutrophils in BAL fluid between the mice treated with Bleo (no iloprost) and those treated with Bleo+iloprost (C and D). Results are expressed as mean ± SEM, n = 5-8 mice each group, ** P < 0.01.