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. 2010 Apr 1;5(4):e9991. doi: 10.1371/journal.pone.0009991

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(A) Frequency distribution of association tests P-values for 553 random SNP (pink bars) and idh SNP3593 (red bar). On the X axis are the log₁₀ (P) values for association tests using mixed-linear model. (B) Comparison between the two alleles at SNP3593 for IDH activity. A combined standardized IDH activity data from the two incubation temperatures is presented. (C) Correlation between IDH total activity and IDH protein quantity across a subset of 35 lines. Each point represents the mean of 3 biological replications.