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The effect of IL11 on TIMP1, TIMP2, and TIMP3 protein production by HTR-8/SVneo (A, C, E) and primary EVTs (B, D). Interleukin 11 (100 ng/ml) had no significant effect on soluble TIMP1 (A, B), TIMP2 (C, D), and cell-bound TIMP3 production (E) during 48 h compared with controls. Data are represented as mean concentrations of TIMPs 1 and 2 (±SEM) from two (primary EVTs) or three (HTR-8/SVneo) independent experiments. Data for TIMP3 are representative of three independent experiments.
