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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Pharmacol Res. 2010 Jan 18;61(5):385–390. doi: 10.1016/j.phrs.2010.01.007

Table 1.

Non-compartmental analysis results for VCR in blood

Non-obese Obese
Dose (μg/mouse) 14.7±0.8 19.7±2.2
Peak VCR (ng/mL) 2,101 6,331
t½,α (min) 4.0 3.5
t½,β (min) 44.5 9.7
t½,γ (hrs) 85.6 60.3
AUC0–24 (ng/mL * hr) 2,846 3,329
AUC0–∞ (ng/mL * hr) 15,384 13,099
VDC (ml/g) 0.238 0.079
VDSS (ml/g) 3.81 3.16