Table 5.

DEGs in cell adhesion molecule (CAM) pathway in Npc1−/− mice.

			AGI*		ILMΔ
Gen symbol	Gene name	Description	FC	P	FC	P
NM_010388	Cd86*Δ	CD86 antigen	1.8	0.016	1.5	0.015
NM_008770	Cldn11*Δ	claudin 11	−1.5	0.020	−1.3	0.004
NM_019500	Cldn14*Δ	claudin 14	−1.4	0.046	−1.4	0.013
NM_010398	H2-T23*Δ	histocompatibility 2, T region locus 23	1.3	0.021	1.5	0.001
BC008626	Icam1*Δ	intercellular adhesion molecule	2.5	0.001	1.8	0.003
NM_013566	Itgb7*Δ	integrin beta 7	−1.6	0.013	−15	0.032
NM_010758	Mag*Δ	myelin-associated glycoprotein	−1.5	0.006	−1.4	0.022
XM_135954	4930468A15RikΔ	RIKEN cDNA4930468A15 gene	N.A.	N.A.	1.6	0.000
NM_009845	Cd22*	CD22 antigen	7.5	0.000	N.A.	N.A.
NM_007642	Cd28*	CD28 antigen	−18	0.018	N.A.	N.A.
NM_009902	Cldn3Δ	claudin 3	N.A.	N.A.	1.7	0.005
NM_008199	H2-Bl*	histocompatibility 2, blastocyst	1.9	0.012	N.A.	N.A.
NM_010380	H2-D1Δ	histocompatibility 2, D region locus 1	N.A.	N.A.	1.9	0.002
BC080756	H2-K1*	histocompatibility 2, K1, K region	1.5	0.016	N.A.	N.A.
NM_010389	H2-ObΔ	histocompatibility 2, O region beta locus	N.A.	N.A.	−16	0.014
NM_207648	H2-Q6Δ	histocompatibility 2, Q region locus 6	N.A.	N.A.	1.5	0.030
NM_023124	H2-Q8Δ	histocompatibility 2, Q region locus 8	N.A.	N.A.	1.3	0.006
NM_008404	Itgb2*	integrin beta 2	2.0	0.002	N.A.	N.A.
NM_023277	Jam3*	junction adhesion molecule 3	−1.4	0.013	−1.2	0.218
XM_129565	Mpzl1Δ	myelin protein zero-like 1	N.A.	N.A.	1.3	0.029
NM_011210	Ptprc*	protein tyrosine phosphatase, receptor type, C	2.0	0.015	−1.2	0.503
AK041480	SpnΔ	sialophorin	N.A.	N.A.	−1.4	0.022