Figure 4.
Detailed LOD score plots for the overlapping QTLs on chromosome1 (A), 15 (B), and 9 (C), using the data from F2 males and females with sex treated as an interactive covariate. Solid lines represent atherosclerotic lesion sizes in aortic arch (black) and root (green), angle (red), and mean diameter of aortic arch (blue). Dashed lines represent plasma levels of cholesterol (red), triglyceride (blue), and HDL-C (green). Horizontal dashed lines and alternate long and short dash lines represent significant (p=0.05) and suggestive (p=0.63) levels for arch lesion size (A and B) or root lesion size (C).