Table 1.

Diagnostic criteria for major depression

Depressed mood

Decreased interest in pleasurable activities and ability to experience pleasure (anhedonia)

Weight loss or weight gain, increased or decreased appetite

Insomnia or hypersomnia

Psychomotor agitation or retardation

Fatigue or loss of energy

Feelings of hopelessness, worthlessness and guilt

Decreased ability to think or concentrate

Recurrent thoughts of death and suicide

Decreased ability to perform daily tasks efficiently

Diagnostic for major depression is made according to the criteria defined by the Diagnostic Statistical Manual of Mental Disorders if a minimum of five symptoms (including at least one of the bolded symptoms) from the above list have been present during the same 2 week period and disrupt normal occupational and social functioning. (Bolded symptoms are considered cardinal and more specific signs of depression.)