TABLE 1.

Features of Hepatocellular Nodule Histotypes

		Diameter (cm)
Histotype	n	Mean ± SD	Range	≤ 2 (n)	> 2 (n)
Hepatocellular carcinoma	84a	3.1 ± 0.9	1–5	20	64
Other malignant histotype	12b	2.5 ± 1.6	3–4	5	7
Dysplastic nodule	13c	1.9 ± 0.6	1–3	7	6
Regenerative nodule	57	1.9 ± 0.8	1–4	46	11
Hemangioma	42d	1.9 ± 0.7	1–3	31	11
Focal nodular hyperplasia	2	4 ± 0	4	0	2
Hepatocellular adenoma	1	4 ± 0	4	0	1
Pseudotumor	25e	1.7 ± 0.6	1–3	21	4
Total	236	2.3 ± 1.1	1–5	130	106

^aNodules ≤ 2 cm (n = 20) included 16 well-differentiated and four moderately or poorly differentiated hepatocellular carcinomas. Nodules > 2 cm (n = 64) included eight well-differentiated and 56 moderately or poorly differentiated hepatocellular carcinomas.

^bOther histotypes were intrahepatic cholangiocarcinoma (n = 6), metastatic lesion (n = 4), nodular lymphoma (n = 1), and epithelioid hemangioendothelioma (n = 1).

^cDysplastic nodules had a low- (n = 8) or high-grade (n = 5) pattern.

^dLiver hemangioma had a hypervascular (n = 35) or thrombotic–fibrotic (n = 4) pattern at histologic examination. Other hemangiomas (n = 3) had endothelium-lined vascular channels.

^ePseudotumor included focal fibrosis (n = 11), focal fatty changes or focal fat sparing (n = 8), intrahepatic arterioportal nontumorous shunt (n = 5), and focal lymphoid hyperplasia (n = 1).