Shown are the Louisville Swim Scale (LSS) scores, over time, for swim-trained and untrained animals assessed with (A) and without (B) supplementary cutaneous feedback from the Phase 1 study. For comparison purposes, the 42-day LSS scores are shown for our previously published study (Smith et al., 2006a), where animals were swim trained starting at 2 weeks post-injury. The dashed line represents an LSS score of 6, which marks the transition from low to moderate swimming and the recovery of at least occasional hindlimb movement occurring 6–50% of the 4-min assessment period.