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Effects of POLQ knockdown on γH2AX foci. A) In unirradiated SQ20B cells POLQ knockdown has no effect on γH2AX foci formation. B) γH2AX foci in SQ20B cells transfected with either NT or POLQ siRNA fixed 24 hours after receiving 4Gy. C) Increase in proportion of cells with >7 γH2AX foci in irradiated SQ20B cells with POLQ knockdown. **, P < 0.01 unpaired two sided t-test.
