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Demonstration of the absence of off-target effects. A) T24 cells transfected with either 50nM POLQ pool of siRNA (SER=1.18), or 25nM of each individual siRNA strand. **, P < 0.01 unpaired two sided t-test. B) Relative expression of POLQ normalised to cells treated with NT siRNA as determined by qRT-PCR.
