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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Semin Nephrol. 2010 Mar;30(2):150–163. doi: 10.1016/j.semnephrol.2010.01.006

Table 1.

Systolic and diastolic blood pressure reductions by angiotensinogen (AGT) genotypes after intervention in three clinical trials.

AGT G-6A AA GA GG AA-GG
difference
TOHP Na reduction, mmHg -2.7/-2.2 -1.3/-0.7 -0.2/1.1 -2.5/-1.5
TOHP wt. loss, mmHg -3.5/-2.4 -0.9/-1 -1.1/0.3 -2.6/-1.4
SAGA salt diet, mmHg -8.6/-3.9 -9.0/-5.2 -5.3/-1.0 -3.3/-2.9
DASH fruit/veg. diet, mmHg -5.2/-3.0 -2.3/-1.2 -1.3/0.3 -3.9/-3.3
DASH diet, mmHg -6.9/-3.5 -5.6/-3.2 -2.8/0.2 -4.1/-3.7

TOHP: Trials of Hypertension Prevention II (36); SAGA: Dutch clinical trial using SAGA salt (38); DASH: Dietary Approaches to Stop Hypertension (37).