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. Author manuscript; available in PMC: 2011 Feb 5.
Published in final edited form as: Cell Stem Cell. 2010 Feb 5;6(2):153–166. doi: 10.1016/j.stem.2009.12.014

Figure 6. PCL2 binds a subset of PRC2 targets and is associated with 3meH3K27.

Figure 6

A) Binding profiles of 14 PCL2 and PRC2 targets. Genomic range in each panel extends from -10kb from the TSS to the end of the gene. B-F) ChIP-qPCR validation of 14 selected promoter regions in both wild type and knockdown cells for PCL2, EZH2, EED, SUZ12 and 3meH3K27. Values are calculated as the fold enrichment above a control without antibody. Wild-type vs. knockdown samples were normalized to a fraction of the Input material for each primer set tested to adjust for differences in starting amounts.