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Receptor occupancy and free ligand concentration during the recovery phase of buffered diffusion. Simulation parameters were the same as used in Fig. 2, except that at t = 5 s, the external ligand concentration was clamped to 0. Fig. S2 shows the corresponding graphs for free ligands. (A) Unliganded (R) and liganded (RC) receptors as a function of time. (B) Unliganded (R) receptors as a function of time within the different segments of the box synapse.
