Table 1.

Standard values of the parameters used in the simulations

Parameter	Standard value
Ligand association rate, ${\ell }_{+}$	1 × 108 M−1 s−1
Ligand dissociation rate, ${\ell }_{-}$	3 s−1
Ligand diffusion coefficient, D	1 × 10−6 cm2 s−1
Ligand concentration, [C]	450 nM (15 × Leq)
Receptor density, ρ	104μm−2
Synaptic cleft thickness, tcleft	0.05 μm