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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Arthritis Rheum. 2009 Dec;60(12):3633–3641. doi: 10.1002/art.24980

Figure 4. Increased autoantibodies in female SJL IL-12 TG mice.

Figure 4

Plasma samples were collected and autoantibody levels were measured as described in the Material and Methods section. Plasma analysis (N=5 for WT and N=9 for TG) showed increased ANA levels (A) and age-dependent increased levels of anti-La/SSB (C). The levels of anti-Ro(60-kDa)/SSA (B) showed a trend to increased levels in TG compared to WT mice, but was not significant. Data shown are mean values +/− SD. Significant differences are indicated (*) and were determined by unpaired student's t-test. WT = wild type, TG = IL-12 transgenic.