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. Author manuscript; available in PMC: 2010 Apr 5.
Published in final edited form as: J Pharm Sci. 2010 Feb;99(2):730–740. doi: 10.1002/jps.21863

Figure 3.

Figure 3

Low and high magnification cryo-SEM images of the stratum corneum of natively hydrated porcine skin tissue. a: The stratum corneum consists of a dense outer layer and a less dense inner layer (each arrow marks the location of a corneocyte cell in the inner layer). b: The inner layers consist of irregular shaped corneocyte cells (indicated by arrows). Small gaps between corneocytes in b are artifacts of cryo-fracturing. c: The outer layer consists of densely packed flat sheets of corneocyte cells.