TABLE 4.
Comparison of the imprecision data from different laboratory methodsa
| Method | Manufacturer | CV% (no. of replicates) |
||
|---|---|---|---|---|
| Within-run imprecision | Between-run imprecision | Total imprecisionb | ||
| Glucose, automated (Cobas Integra 400 Plus) | Roche (data obtained from HUSLAB clinical chemistry laboratory evaluation) | 0.7-2 (36-188) | 1.2-2.4 (36-188) | 1.7-3.1 |
| Axsym HIV Ab/Ag Combo, automatedc | Abbott | 3.7-7.2 | 4.6-9.3 | NR |
| TSH receptor autoantibodies, manual method | RSR Limited, Cardiff, UK | 4.2-5.5 (21) | 8.7-8.8 (25) | NR |
| Anti-C1q autoantibodies, manual method | Bűhlmann Laboratories Ag, Schönenbuch, Switzerland | 4.4-7.1 | 7.1-14.3 | NR |
| MPO ANCA, manual method | Euro-Diagnostica, Malmö, Sweden | 4-12 (8) | 4-25 (6) | NR |
| ImmuKnow manual method | Cylex, Columbia, MD | 7.7-15.6 (5)d | NR | |
a
The data are collected from the manufacturers' kit instructions. Data for the glucose measurement are taken from the internal evaluation of Cobas Integra 400 Plus at HUSLAB, Department of Clinical Chemistry.
b
NR, not reported.
c
This study had 10 sites, 10 instruments, and 2 or 3 different lots (total number of replicates, 189).
d
Nonconventional study design.