TABLE 1.
Hematological values for sickle cell disease patients in steady state or VOC and for NHC
| Variable | Value (mean ± SD) for: |
Pa | ||
|---|---|---|---|---|
| HbSS patients |
NHC (n = 20) | |||
| VOC (n = 27) | Steady state (n = 20) | |||
| Packed cell vol | 24.7 ± 5.2 | 25.1 ± 5.1 | 40.0 ± 5.2 | <0.05* |
| White blood cell count (109/liter) | 11.2 ± 6.4 | 9.9 ± 4.6 | 6.7 ± 2.1 | <0.05*§ |
| Differential count (% of white blood cells) | ||||
| Neutrophils | 63.3 ± 10 | 57.3 ± 9.7 | 50.45 ± 9.6 | <0.05*§ |
| Lymphocytes | 34.7 ± 10 | 40.3 ± 11 | 46.1 ± 9 | <0.05*§ |
| Eosinophils | 3.00 ± 2 | 3.86 ± 3 | 3.01 ± 2 | >0.05 |
| Basophils | 3.4 ± 2 | 2.75 ± 1 | 2.9 ± 0.9 | >0.05 |
| Platelet count (109/liter) | 242 ± 51 | 233 ± 42 | 267 ± 56 | >0.05 |
| Reticulocytes (%) | 4.4 ± 4 | 3.6 ± 1.6 | ||
a
Determined by two-tailed Student t tests. *, significant (P < 0.05) statistical difference between values for patients in VOC and those for normal healthy controls; §, significant (P < 0.05) statistical difference between values for SCD patients in steady state or VOC and those for NHC.