TABLE 1.
Comparison of the enzyme immunoassay and Liaison test systems for detection of borrelial IgM and IgG in the sera of patients with different clinical diagnoses
| Group and LIA resulta | No. (%) with the indicated EIA result |
|||||||
|---|---|---|---|---|---|---|---|---|
| IgM |
IgG |
|||||||
| Pos | Bord | Neg | All | Pos | Bord | Neg | All | |
| LNB | ||||||||
| Pos | 13 (38.2) | 1 (2.9) | 5 (14.7) | 19 (55.9) | 22 (64.7) | 0 | 3 (8.8) | 25 (73.5) |
| Bord | 1 (2.9) | 0 | 1 (2.9) | 2 (5.9) | 0 | 1 (2.9) | 1 (2.9) | 2 (5.8) |
| Neg | 0 | 1 (2.9) | 12 (35.3) | 13 (38.2) | 0 | 1 (2.9) | 6 (17.4) | 7 (20.6) |
| All | 14 (41.2) | 2 (5.9) | 18 (52.9) | 34 (100) | 22 (64.7) | 2 (5.9) | 10 (29.4) | 34 (100) |
| sLNB | ||||||||
| Pos | 4 (14.8) | 1 (3.7) | 7 (25.9) | 12 (44.4) | 11 (40.7) | 0 | 4 (14.8) | 15 (55.6) |
| Bord | 0 | 0 | 2 (7.4) | 2 (7.4) | 0 | 0 | 1 (3.7) | 1 (3.7) |
| Neg | 1 (3.7) | 0 | 12 (44.4) | 13 (48.1) | 0 | 0 | 11 (40.7) | 11 (40.7) |
| All | 5 (18.5) | 1 (3.7) | 21 (77.8) | 27 (100) | 11 (40.7) | 0 | 16 (59.3) | 27 (100) |
| TBE | ||||||||
| Pos | 0 | 0 | 4 (12.5) | 4 (12.5) | 12 (37.5) | 2 (6.3) | 1 (3.1) | 15 (46.9) |
| Bord | 0 | 0 | 2 (6.3) | 2 (6.3) | 0 | 0 | 1 (3.1) | 1 (3.1) |
| Neg | 0 | 1 (3.1) | 25 (78.1) | 26 (81.2) | 2 (6.3) | 0 | 14 (43.8) | 16 (50.0) |
| All | 0 | 1 (3.1) | 31 (96.9) | 32 (100) | 14 (43.8) | 2 (6.3) | 16 (50.0) | 32 (100) |
a
LIA, Liaison test; LNB, Lyme neuroborreliosis; sLNB, suspected Lyme neuroborreliosis; TBE, tick-borne encephalitis; Pos, positive; Bord, borderline; Neg, negative.