TABLE 2.
Comparison of the enzyme immunoassay and Liaison test systems for detection of borrelial IgM and IgG in the CSF of patients with different clinical diagnoses
| Group and LIA resulta | No. (%) with the indicated EIA result |
|||||||
|---|---|---|---|---|---|---|---|---|
| IgM |
IgG |
|||||||
| Pos | Bord | Neg | All | Pos | Bord | Neg | All | |
| LNB | ||||||||
| Pos | 7 (20.6) | 0 | 14 (41.2) | 21 (61.8) | 14 (41.2) | 0 | 6 (17.6) | 20 (58.8) |
| Bord | 0 | 0 | 1 (2.9) | 1 (2.9) | 0 | 0 | 0 | 0 |
| Neg | 0 | 0 | 12 (35.3) | 12 (35.3) | 0 | 0 | 14 (41.2) | 14 (41.2) |
| All | 7 (20.6) | 0 | 27 (79.4) | 34 (100) | 14 (41.2) | 0 | 20 (58.8) | 34 (100) |
| sLNB | ||||||||
| Pos | 0 | 0 | 0 | 0 | 0 | 0 | 4 (14.8) | 4 (14.8) |
| Bord | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Neg | 0 | 0 | 27 (100) | 27 (100) | 0 | 0 | 23 (85.2) | 23 (85.2) |
| All | 0 | 0 | 27 (100) | 27 (100) | 0 | 0 | 27 (100) | 27 (100) |
| TBE | ||||||||
| Pos | 0 | 0 | 4 (12.5) | 4 (12.5) | 1 (3.1) | 0 | 7 (21.9) | 8 (25) |
| Bord | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Neg | 0 | 0 | 28 (87.5) | 28 (87.5) | 0 | 0 | 24 (75) | 24 (75) |
| All | 0 | 0 | 32 (100) | 32 (100) | 1 (3.1) | 0 | 31 (96.9) | 32 (100) |
a
LIA, Liaison test; LNB, Lyme neuroborreliosis; sLNB, suspected Lyme neuroborreliosis; TBE, tick-borne encephalitis; Pos, positive; Bord, borderline; Neg, negative.