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(a) Mean relative levels of expression of Foxp3 (± standard error of the mean) in PBMCs stimulated with HPV-16 VLPs or anti-CD3/CD28 compared with that in cells treated with medium alone. (b) Mean relative levels of expression of Foxp3 (± standard error of the mean) in PBMCs treated with E2 and P4 compared with that in non-hormone-treated cells stimulated with HVP 16 VLPs, anti-CD3/CD28, or medium alone. *, P < 0.05, by the Wilcoxon rank-sum test.
