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In vivo ED50 scores
| Strain | FLC MIC (μg/ml) | ED50 (mg/kg) determined on the basis of: |
Median ED50 (mg/kg) | ||
|---|---|---|---|---|---|
| Kidney burden | Wt change | Outcome score | |||
| DSY294-CIp10 | 0.25 | 10 | 1.0 | 3.5 | 3.5 |
| DSY296-CIp10 | 64 | >200 | 120 | 200 | 200 |
| DSY3083-CIp10 | 4 | 10 | 10 | 10 | 10 |
| DSY3606 | 4 | 120 | 120 | 120 | 120 |
| DSY3706 | 0.25 | 3.5 | 1 | 3.5 | 3.5 |
