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Number of viable bacteria (CFU/ml) at necropsy in lung and spleen tissues of TB-infected guinea pigs receiving the different treatments daily for 4 weeks (average ± standard deviation; n = 6). +, significantly lower than any other group (P < 0.0001); $, significantly lower than low-dose group, untreated, control, or placebo (P = 0.0027); #, significantly lower than untreated control or placebo (P = 0.0084); *, significantly lower than placebo (P = 0.0074).
