Exposure to prolonged restraint significantly changes community structure at the genus level. The double dendrogram describes the top 15 genera detected among the FWD, RST, and HCC samples. The heat map indicates the relative percentage of the given genera within each sample ID with a color legend and scale provided. The distance of the samples based upon weighted pair linkage and Manhattan distance methods with no scaling is provided at the top of the figure along with a distance score. The bacterial genera and the associated clustering are provided along the y axis, and their associated distance scores are indicated. n = 3 per group on days 1, 3, 5, and 7; n = 8 HCC controls.