FIG. 5.

Exposure to prolonged restraint prior to oral challenge with C. rodentium significantly increased the number of C. rodentium bacteria shed in the stool. Mice were exposed to prolonged restraint on 7 consecutive nights prior to oral challenge with 3 × 10⁸ to 5 × 10⁸ CFU of C. rodentium. The C. rodentium bacteria were then cultured from the stool during the first 21 days of infection. The data are the means ± standard errors of 10 to 16 mice per group. *, P < 0.05 versus both FWD and HCC at the specified time point.