TABLE 6.

Bactericidal activities of bovine cathelicidin peptides against E. coli ATCC 25922 in different biological fluids

Peptide	Bacterial viability (103 CFU/ml)a
	MH brothb	Bovine serumb	Bovine milkc	Bovine wheyc
Control	125 ± 20	115 ± 17	148 ± 43	119 ± 8.6
BMAP-27	<0.2d	<0.2d	107 ± 5.2	0.8 ± 0.6d
BMAP-28	<0.2d	1.5 ± 1.2d	136 ± 21	38 ± 7.2d
Bac5	<0.2d	86.6 ± 22	146 ± 41	124 ± 17
Indolicidin	<0.2d	92 ± 6.4	119 ± 11	143 ± 3.8

^aThe data are means ± standard deviations (SD) of at least four independent experiments.

^bSixty-minute incubation at 4× MIC in MH broth (Table 4).

^cSixty-minute incubation at 8× MIC.

^dStatistically significant difference from control (P < 0.001) as assessed by one-way analysis of variance and the Bonferroni posthoc test.