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HYPK knockdown induces cell death and G1/G0 cell cycle arrest. Flow cytometric cell cycle analysis of HYPK, hNAA10, and hNAA15 knockdown cells was performed at 72 h posttransfection. siLamin- and siGAPDH-treated samples were used as negative controls. (Top panels) No ZVAD treatment. (Bottom panels) ZVAD treatment to inhibit caspase activity and, thereby, induction of caspase-mediated cell death. Experiments were performed three times, and representative values are given.
