TABLE 1.

Summary of monoclonal antibodies to gB used in this study^e

Antibody	Domain	Conformation dependenta	Neutralizingc	Reactive with low pH-treated gBd
				HSV-1 KOS	s-gB
DL16	ND	Y (Oligomer specific)	−	−	−
H126	I	N	+	−	−
H1359	III	N	−	+	+
H1817	VI	N	+	+	+
SS10	IV	Yb	+	+	+
SS55	I	Y	+	−	−
SS106	V	N	+	−	−
SS144	V	Yb	+	−	−
R69	Polyclonal	NA	+	+	+

^aY, reactive with HSV-1 gB under native PAGE conditions but not under denaturing conditions; N, reactive under denaturing conditions only.

^bReactive with native gB and with a small amount of gB under denaturing conditions (7).

^cDefined as reducing HSV-1 entry or plaque formation.

^dgB epitope reactivity was measured by dot blotting, as described in Materials and Methods.

^eData in the first three columns have been previously described (7, 8, 32, 41, 45). ND, not determined; NA, not applicable.