TABLE 2.
Comparison of the deduced proteins from the H. influenzae serotype e capsulation locus of strain 274
| Hie 274 deduced protein, no. of amino acids (aa) | Similar protein (source organism) | Accession no. | % Identity | % Similarity |
|---|---|---|---|---|
| Region I | ||||
| BexA, 217 aa | BexA (H. influenzae serotype f) | AF549211 | 94 | 97 |
| BexA (H. influenzae serotype b) | AF549213 | 94 | 97 | |
| CpxA (Actinobacillus pleuropneumoniae) | CP000687 | 82 | 91 | |
| CtrD (Neisseria meningitidis) | EU038216 | 80 | 89 | |
| CpxA (Mannheimia haemolytica) | AF170495 | 76 | 88 | |
| BexB, 265 aa | BexB (H. influenzae serotype f) | AF549211 | 97 | 99 |
| BexB (H. influenzae serotype b) | M33788 | 95 | 99 | |
| CpxB (Actinobacillus pleuropneumoniae) | CP000687 | 77 | 90 | |
| CpxB (Mannheimia haemolytica) | AF170495 | 74 | 86 | |
| CtrC (Neisseria meningitidis) | EU038216 | 69 | 83 | |
| BexC, 377 aa | BexC (H. influenzae serotype f) | AF549211 | 98 | 98 |
| BexC (H. influenzae serotype b) | AF549213 | 94 | 96 | |
| CpxC (Mannheimia haemolytica) | AF170495 | 76 | 88 | |
| CpxC (Actinobacillus pleuropneumoniae) | CP000687 | 74 | 87 | |
| CtrB (Neisseria meningitidis) | EU038216 | 59 | 79 | |
| BexD, 428 aa | BexD (H. influenzae serotype f) | AF549211 | 91 | 94 |
| BexD (H. influenzae serotype b) | AF549213 | 91 | 95 | |
| CpxD (Actinobacillus pleuropneumoniae) | CP001091 | 73 | 85 | |
| CpxD (Mannheimia haemolytica) | AF170495 | 71 | 84 | |
| CtrA (Neisseria meningitidis) | AF520902 | 55 | 74 | |
| Region II | ||||
| Orf1 (Ecs1), 374 aa | SacA (Neisseria meningitidis) | AL157959 | 71 | 85 |
| Putative UDP-N-acetyl-d-glucosamine 2-epimerase | VIBHAR_00689(Vibrio harveyi) | CP000789 | 63 | 77 |
| VV0341 (Vibrio vulnificus) | BA000037 | 62 | 77 | |
| WecB (Klebsiella pneumoniae) | CP000647 | 61 | 75 | |
| WecB (Escherichia coli) | AE014075 | 61 | 76 | |
| Orf2 (Ecs2), 421 aa | WecB (Mannheimia haemolytica) | AF170495 | 67 | 79 |
| Putative UDP-N-acetyl-d-mannosaminuronic acid dehydrogenase | EcbB (Pasteurella multocida) | AF302466 | 64 | 77 |
| ORF6 (Pseudomonas aeruginosa) | AF498407 | 63 | 77 | |
| WecC (Escherichia coli) | CP000948 | 61 | 75 | |
| SeD_A4308 (Salmonella enterica) | CP001144 | 61 | 74 | |
| Orf3 (Ecs3), 991 aa | BcbC (Pasteurella multocida) | AF169324 | 50 | 69 |
| Putative glycosyltransferase | Msm_1297 (Methanobrevibacter smithii) | CP000678 | 34 | 55 |
| Msp_0219 (Methanosphaera stadtmanae) | CP000102 | 33 | 51 | |
| Eco1C (Escherichia coli) | CP000946 | 31 | 50 | |
| WaaV (Shigella sonnei) | CP000038 | 30 | 50 | |
| Orf4 (Ecs4), 486 aa | BcbD (Pasteurella multocida) | AF169324 | 46 | 65 |
| Unknown function | KfoD (Escherichia coli) | AB079602 | 36 | 55 |
| ORFA (Yersinia enterocolitica) | AY653208 | 21 | 43 | |
| EcbD (Pasteurella multocida) | AF302466 | 26 | 42 | |
| CMU_015760 (Cryptosporidium muris) | XM_002140142 | 26 | 41 | |
| Orf5 (Ecs5), 240 aa | ORF5 (Actinobacillus suis) | AY253301 | 68 | 85 |
| Unknown function | BcbE (Pasteurella multocida) | AF169324 | 65 | 82 |
| BcbE (Photobacterium damselae) | AB074293 | 49 | 67 | |
| SamA (Shewanella amazonensis) | CP000507 | 46 | 64 | |
| VC0395 (Vibrio cholera) | CP000627 | 45 | 63 | |
| Orf6 (Ecs6), 125 aa | ORF6 (Actinobacillus suis) | AY253301 | 77 | 91 |
| Unknown function | BcbF (Pasteurella multocida) | AF169324 | 73 | 89 |
| SamA (Shewanella amazonensis) | CP000507 | 60 | 79 | |
| VC0395 (Vibrio cholerae) | CP000627 | 60 | 78 | |
| BAG50482 (Vibrio parahaemolyticus) | AB353134 | 64 | 78 | |
| Orf7 (Ecs7), 519 aa | BcbG (Pasteurella multocida) | AF302466 | 65 | 77 |
| Unknown function | ORF7 (Actinobacillus suis) | AY253301 | 63 | 78 |
| BcbG (Photobacterium damselae) | AB074293 | 37 | 56 | |
| VC0395 (Vibrio cholerae) | CP000627 | 36 | 55 | |
| BcbG (Zymomonas mobilis) | AE008692 | 36 | 54 | |
| Orf8 (Ecs8), 325 aa | BcbI (Pasteurella multocida) | AF169324 | 64 | 78 |
| Unknown function | ORF2 (Mannheimia haemolytica) | AF170495 | 63 | 74 |
| Fphi_1179 (Francisella philomiragia) | CP000937 | 54 | 73 | |
| Neut_1976 (Nitrosomonas eutropha) | CP000450 | 40 | 63 | |
| NE1334 (Nitrosomonas europaea) | AL954747 | 43 | 63 | |
| Region III | ||||
| HcsA, 595 aa | HcsA (H. influenzae serotype b) | DQ368335 | 96 | 97 |
| HcsA (H. influenzae serotype f) | AF549211 | 95 | 97 | |
| LipA2 (Actinobacillus pleuropneumoniae) | CP000687 | 62 | 75 | |
| PhyA (Mannheimia haemolytica) | AF170495 | 59 | 72 | |
| LipA (Neisseria meningitidis) | AM421808 | 56 | 71 | |
| HcsB, 420 aa | HcsB (H. influenzae serotype b) | DQ368335 | 91 | 95 |
| HcsB (H. influenzae serotype f) | AF549211 | 90 | 94 | |
| PhyB (Actinobacillus pleuropneumoniae) | CP000687 | 65 | 78 | |
| PhyB (Pasteurella multocida) | AF067175 | 64 | 77 | |
| LipB (Neisseria meningitidis) | Z13995 | 55 | 68 |