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. Author manuscript; available in PMC: 2010 Apr 5.
Published in final edited form as: Pharm Biol. 2009;47(1):92–98. doi: 10.1080/13880200802448690

Table 2.

Bacterial load and inflammation induced by Helicobacter pyrlori infection in Mongolian gerbils fed a normal diet or a diet supplemented with standardized ginger extract: prevention study.

CI
AI
Expt. Food Colonies M S Lymph M S C ED E
1 Control 77.83 2.20 1.60 0.80 2.00 1.30 0.80 1.80 1.80
1 Ginger 56.71 1.00* 0.25** 0.25 0.60* 0.00** 0.25* 0.25** 0.00**

Seven animals per arm; gerbils were fed a normal diet throughout (Purina 5001 chow; control) or a normal diet supplemented with 100 mg ginger extract /kg body weight in daily rations for 3 weeks prior to inoculation and 6 weeks after (9 weeks total); inflammation was graded using the criteria of Table 1. Colonies = bacterial load in log cfu per stomach; CI = chronic inflammation; Lymph = Lymphocyte infiltration; AI = acute inflammation; M = mucosal; S = submucosal; C = cryptitis; ED = epithelial cell degeneration; E = erosion. Mean value was significantly different from that of the control group:

*

P<0.05

**

P<0.01.