Table 2.
Bacterial load and inflammation induced by Helicobacter pyrlori infection in Mongolian gerbils fed a normal diet or a diet supplemented with standardized ginger extract: prevention study.
CI |
AI |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Expt. | Food | Colonies | M | S | Lymph | M | S | C | ED | E |
1 | Control | 77.83 | 2.20 | 1.60 | 0.80 | 2.00 | 1.30 | 0.80 | 1.80 | 1.80 |
1 | Ginger | 56.71 | 1.00* | 0.25** | 0.25 | 0.60* | 0.00** | 0.25* | 0.25** | 0.00** |
Seven animals per arm; gerbils were fed a normal diet throughout (Purina 5001 chow; control) or a normal diet supplemented with 100 mg ginger extract /kg body weight in daily rations for 3 weeks prior to inoculation and 6 weeks after (9 weeks total); inflammation was graded using the criteria of Table 1. Colonies = bacterial load in log cfu per stomach; CI = chronic inflammation; Lymph = Lymphocyte infiltration; AI = acute inflammation; M = mucosal; S = submucosal; C = cryptitis; ED = epithelial cell degeneration; E = erosion. Mean value was significantly different from that of the control group:
P<0.05
P<0.01.