Table 2.
Proportions of mixed-clone infections, mean number of microsatellite alleles per locus, genetic diversity (virtual heterozygosity [HE]), and linkage disequilibrium (standardized index of association [IS A]) in malaria parasite populations from rural Amazonia
| ISA by infection typed |
|||||
|---|---|---|---|---|---|
| Parasite species | Multiple-clone infections (%) | Alleles per locus, mean±S.E. (range) | HE mean±S.E. (range) | All | Those with unique haplotypes |
| P. falciparuma | 13·9 | 2·8±0·4 (2–4) | 0·43±0·06 (0·09–0·67) | 0·088 (n=44) | 0·032 (n=31) |
| P. falciparumb | 21·8 | 3·3±0·4 (2–5) | 0·46±0·04 (0·20–0·68) | 0·070 (n=55) | 0·028 (n=40) |
| P. vivaxc | 49·0 | 6·9±0·8 (3–14) | 0·71±0·04 (0·34–0·88) | 0·202 (n=49) | 0·119 (n=39) |
a
44 samples collected in Granada between 2004 and 2006.
b
44 samples collected in Granada between 2004 and 2006 and 11 samples collected in Plácido de Castro in 2008.
c
49 samples collected in Granada between 2004 and 2005 and genotyped with 14 microsatellites (Ferreira et al. 2007).
d
All IS A values were significantly larger than zero (P = 0·001), denoting significant multilocus linkage disequilibrium.