Table 5.
Adjusted prevalence of CKD, by MDRD Study equation estimation of GFR, among those with prediabetes versus no diabetes, by selected characteristics, NHANES 1999 through 2006
| Characteristic | % with Stages 1 through 4 CKD (95% CI) |
||
|---|---|---|---|
| Prediabetes | No Diabetes | Pa | |
| Overall | 17.1 (15.9 to 18.5) | 11.8 (10.5 to 13.3) | <0.001 |
| Age (years) | |||
| 20 to 59 | 11.7 (10.6 to 12.9) | 6.3 (5.4 to 7.4) | 0.001 |
| ≥60 | 36.9 (34.3 to 39.5) | 31.5 (28.4 to 34.8) | 0.164 |
| Gender | |||
| male | 14.3 (12.9 to 15.8) | 8.1 (6.9 to 9.6) | 0.172 |
| female | 18.6 (17.0 to 20.4) | 13.3 (11.5 to 15.4) | 0.001 |
| Race/ethnicityb | |||
| non-Hispanic white | 15.8 (14.4 to 17.2) | 10.7 (9.3 to 12.3) | 0.005 |
| non-Hispanic black | 20.4 (18.3 to 22.7) | 12.9 (10.9 to 15.3) | 0.036 |
| Mexican American | 14.5 (12.7 to 16.6) | 7.6 (6.0 to 9.5) | 0.035 |
| BMI (kg/m2) | |||
| <30 | 14.6 (13.1 to 16.3) | 9.7 (8.5 to 11.2) | 0.017 |
| ≥30 | 17.9 (15.8 to 20.2) | 11.5 (9.6 to 13.8) | 0.008 |
| Self-reported hypertension | |||
| yes | 29.5 (27.1 to 31.9) | 21.6 (18.7 to 24.8) | 0.011 |
| no | 10.7 (9.3 to 12.4) | 7.1 (6.0 to 8.3) | 0.121 |
CKD defined by MDRD Study equation–calculated eGFR <60 ml/min per 1.73 m2 or single micro/macroalbuminuria measurement; prediabetes, FPG ≥100 and <126 mg/dl and no self-report of diabetes; no diabetes, FPG <100 mg/dl and no self-report of diabetes. BMI, body mass index; CI, confidence interval.
Prevalence estimates adjusted for age, gender, and race/ethnicity, excluding variables being examined (e.g., age-stratified prevalence adjusted for gender and race/ethnicity only). Models that produced prevalence estimates included individuals in all four categories of diabetes status; models that produced P values included only those with prediabetes or no diabetes.
Prevalence for other race/ethnicity not shown because of small sample sizes, but individuals in category are included in all analyses.