Table 3.
Characteristics of Treated and Comparison Groups
| Cases (N=30) | Comparison Group (N=117) | p-value* | |
|---|---|---|---|
| Age at diagnosis | 0.15 | ||
| Median | 61 years | 63 years | |
| Range | (28 – 76 yrs) | (42 – 89 yrs) | |
| Clinical Stage at diagnosis (Rai) | 0.58 | ||
| 0 | 17 (57%) | 55 (47%) | |
| I | 11 (37%) | 48 (41%) | |
| II | 2 (7%) | 15 (12%) | |
| Risk Group (hierarchical) | 0.24 | ||
| 17p− | 9 (30%) | 19 (16%) | |
| 11q− | 8 (27%) | 39 (33%) | |
| UM + ZAP-70+ and/or CD38+ | 13 (43%) | 59 (50%) | |
UM indicates unmutated, hierarchical indicates risk stratification with use of single highest risk prognostic factor (17p13− > 11q22− > IgVH UM and ZAP-70/CD38+).
*
Wilcoxon rank sum or Fisher’s exact p-value