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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Mech Ageing Dev. 2010 Jan 18;131(2):144–155. doi: 10.1016/j.mad.2010.01.002

Fig. 3.

Fig. 3

Specific peptidase activities showed the statistically significant decline only in the cytosolic fraction when older mice were compared to 6 mos old animals. The microsomes associated proteasomes exhibited no clear change in peptidase activities. Nuclear proteasomes revealed weak declining trends. Although not statistically significant, the strongest declining trend in this fraction was demonstrated by T-L activity. Specific activity was calculated as a reaction rate per amount of total protein in the corresponding fraction what approximates a total catalytic challenge potentially faced by proteasome.