Table 3. Non-Mood Outcome Measures at Week 24&.
Measure | Baseline | Week 24 | Treatment Effect* (χ2[df], p value) |
||
---|---|---|---|---|---|
Sertraline | Placebo | Sertraline | Placebo | ||
NPI Non-Mood | 10 (5, 19) | 9.5 (3.75, 14) | 6 (2, 11) | 4 (0, 12) | χ2=7.9 (4), 0.10 |
ADRQL | 81.7 (72.8, 88.5) | 81.1 (73.2, 88.4) | 87.1 (80.4, 92.2) | 85.7 (73.3, 92.5) | χ2=0.9 (2), 0.30 |
ADCS-ADL | 55 (44.5, 66.5) | 56.5 (47.75, 66) | 56 (41.5, 66) | 53.5 (34, 67) | χ2<0.001 (1), 0.99 |
MMSE | 21 (17, 25) | 19.5 (15, 23.25) | 21 (16.5, 24) | 20 (14.75, 24) | χ2= 0.5 (1),0.50 |
The table shows the median (1st, 3rd quartiles) of the data from the first imputation
Likelihood ratio statistic using data from all study visits comparing a model including interaction terms for treatment group by time variables versus a model without these interaction terms.