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. 2010 Feb 22;28(9):1566–1572. doi: 10.1200/JCO.2009.25.4680

Table 2.

Distribution of Histologically Confirmed Superficial Cancer According to Lesion in the Head and Neck Region and the Esophagus

Variable Primary WLI (n = 162)
Primary NBI (n = 158)
P
No. % 95% CI No. % 95% CI
Head and neck region
    No. of patients 12 7 3.3 to 11.4 14 9 4.4 to 13.3 .66
    No. of lesions per patient
        1 12 7 3.3 to 11.4 14 9 4.4 to 13.3 > .999
        ≥ 2 1 0.6 −0.6 to 1.8 1 0.6 −0.5 to 1.9
    Total No. of superficial neoplasias 13 15
    Size threshold, mm
        < 10 7 10 .50
        11-20 5 5
        ≥ 21 1 0
    Histologic diagnosis
        High-grade intraepithelial neoplasia or carcinoma in situ 10 15 .09
        Microinvasive cancer 3 0
Esophagus
    No. of patients 58 36 28.4 to 43.2 63 40 32.2 to 47.6 .49
    No. of lesions per patient
        1 39 24 17.4 to 30.7 43 27 20.3 to 34.2 > .999
        ≥ 2 19 12 6.7 to 16.7 20 13 7.4 to 17.9
    Total No. of superficial cancers 105 107
    Size threshold, mm
        < 10 18 18 .91
        11-20 21 19
        ≥ 21 66 70
    Histologic diagnosis
        High-grade intraepithelial neoplasia or carcinoma in situ 73 84 .16
        Microinvasive cancer 32 23

Abbreviations: WLI, white light imaging; NBI, narrow band imaging.