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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: J Pharmacol Toxicol Methods. 2010 Jan 22;61(2):136–145. doi: 10.1016/j.vascn.2010.01.001

Table 2.

HET-CAM Irritation Score Classification System

Substance score Category of IS classification
0 - 0.9 Nonirritant or practically none
1 - 4.9 Weak or slight irritation
5 - 8.9 or 5 - 9.9 Moderate irritation
9 - 21 or 10 – 21 Strong or severe irritation

Abbreviations: IS = irritation score