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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Biol Psychiatry. 2010 Jan 4;67(8):730–736. doi: 10.1016/j.biopsych.2009.11.015

Figure 4.

Figure 4

Effects of removal of a cocaine-associated cue on self-administration behavior in sign-trackers (n=14) and goal-trackers (n=16). (a) The mean ± SEM number of cocaine infusions (0.2 mg/kg/infusion) per minute in sign-trackers and goal-trackers in the presence of the cocaine cue (sessions 1–3, 6–9) and when the light cue was not presented along with the injection of cocaine (sessions 4–5). (b) The rate of cocaine self-administration (infusions/min) for individual animals averaged over the baseline period (cocaine cue present, sessions 1–3) and the cue removal sessions (sessions 4–5). *, indicates a significant group difference, p < 0.05.