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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Biologicals. 2009 Nov 6;38(2):278–283. doi: 10.1016/j.biologicals.2009.09.007

Figure 1.

Figure 1

Virus-induced mortality in mice assessed over a 28 day period following intracerebral inoculation with different vaccinia virus strains. Due to high mortality following administration of 104 pfu of the Lister and Copenhagen strains and following administration of 103 pfu of the IHD-J and WR strains, higher doses of these viruses were not tested to avoid unnecessary use of animals. In addition, for humane purposes, moribund mice were euthanized and included in mortality counts.