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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Biologicals. 2009 Nov 6;38(2):278–283. doi: 10.1016/j.biologicals.2009.09.007

Table 1.

Vaccinia virus strain specific mouse LD50

Virus Dose
(pfu or ffu)
Mortality* LD50
(pfu or ffu)
MVA 100 0/12 ≥ 100,000
101 0/12
102 0/12
103 0/12
104 0/12
105 0/21
Dryvax® 100 0/22 44.7
101 11/36
102 26/39
103 9/12
104 10/10
105 12/12
Lister 100 5/32 11.2
101 16/34
102 27/32
103 12/12
104 10/10
Copenhagen 100 6/32 6.6
101 18/33
102 31/33
103 10/10
104 12/12
WR 100 11/29 1.5
101 25/25
102 20/20
103 12/12
IHD-J 100 21/34 1.0
101 20/20
102 34/34
103 12/12
Medium - 0/20 -
*

For humane purposes, moribund mice were euthanized and included in mortality counts.