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. Author manuscript; available in PMC: 2011 May 1.
Published in final edited form as: Exp Neurol. 2009 May 21;223(1):112–118. doi: 10.1016/j.expneurol.2009.05.022

Figure 2.

Figure 2

Electronmicroscopic evaluation of P4 and adult mouse median nerves. A: Normal P4 median nerve. The majority of cross-sectional area is occupied by Schwann cells and myelination is underway. B: Wallerian degeneration proceeds rapidly in P4 nerve and is nearly complete after 5 days. Clumps of black myelin debris remain. C: Schwann cells are morphologically normal after 5 days in culture. D: Normal adult median nerve. E: After 5 days in culture there is clumping of axoplasm (arrows), but most myelin profiles appear normal. Wallerian degeneration is delayed when blood-borne inflammatory cells are not available. F: Adult Schwann cells are morphologically normal after 5 days in culture.