Table 2.

Effect of heparin on duration of peripheral venous catheter patency. Figures are means with or without SD unless stated otherwise

Author	Heparin	Patency duration (hours)		Difference (hours) for heparin − control
		Heparin	Control
Kleiber et al, 199311	10 U every 6 hours*	38.2 (40)	35.4 (30)	2.8
Hamilton et al, 198815	100 U every 8 hours*	44.3 (19)	45.4 (18)	−0.9
Daniell et al, 197317	1 U/ml infused	88.5	57.6	30.9
Alpan et al, 198418	1 U/ml infused	58.7 (45)	26.1 (20)	32.6†
Wright et al, 199520	1 U/ml infused	97‡	43‡	54.0†
Moclair et al, 199110	1 U/ml infused	69‡	31‡	38.0

^*Flush solution (control or heparin) used after medications in addition to or in place of scheduled flush.  

^†Authors report P<0.05.  

^‡Medians.