Table 5.
Genes that are changed in the same direction in the cell line model and the ovarian cancer tissue model
| common genes | Description | IGROV1 _CP | IGROV1 | 12344 (Chemo- R) | 12628 (chemo- S) |
|---|---|---|---|---|---|
| CYP26B1 | Cytochrome P450, family 26, subfamily B, polypeptide 1 | 46 | 0 | 67 | 2 |
| AP2B1 | Adaptor-related protein complex 2, beta 1 subunit | 52 | 8 | 110 | 14 |
| PSMB1 | Proteasome (prosome, macropain) subunit, beta type, 1 | 151 | 70 | 976 | 265 |
| LYPLA2 | Lysophospholipase II | 182 | 96 | 199 | 24 |
| MRC2 | Mannose receptor, C type 2 | 64 | 154 | 101 | 375 |
| FHL1 | Four and a half LIM domains 1 | 36 | 2 | 489 | 46 |
| RPL26L1 | Ribosomal protein L26-like 1 | 20 | 0 | 160 | 46 |
| NEDD4L | Neural precursor cell expressed, developmentally down-regulated 4- like | 44 | 8 | 48 | 8 |
| SP100 | SP100 nuclear antigen | 23 | 0 | 49 | 12 |
| DUSP1 | Dual specificity phosphatase 1 | 168 | 53 | 578 | 93 |
| PABPC1 | Poly(A) binding protein, cytoplasmic 1 | 5033 | 7569 | 1232 | 3655 |
| SDHA | Succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 137 | 51 | 40 | 6 |
| ADK | Adenosine kinase | 55 | 0 | 61 | 17 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 98 | 23 | 139 | 35 |
| TP53INP2 | Tumor protein p53 inducible nuclear protein 2 | 37 | 0 | 61 | 14 |
| LAMB1 | Laminin, beta 1 | 726 | 234 | 78 | 18 |
| PHGDH | Phosphoglycerate dehydrogenase | 42 | 0 | 219 | 54 |
| SLC25A1 | Solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 103 | 293 | 25 | 100 |