Table 1.
High predictive power of BRAF mutation for recurrence of papillary thyroid cancer [recurrent cases/total cases (%)]
| Patient Groups | BRAF Mutation (+) | BRAF Mutation (−) | Clinical Follow-up Months (median) | Odds Ratio (95% CI) | P value | References |
|---|---|---|---|---|---|---|
| American | 23/92 (25) | 9/96 (9) | 15 | 3.37 (1.47–7.74) | 0.006 | Xing et al, 200551 |
| Korean | 32/149 (21) | 4/54 (7) | 88 | 3.42 (1.15–10.18) | 0.022 | Kim et al, 200652 |
| Spanish | 9/28 (32) | 3/39 (8) | 36 | 5.68 (1.37–23.52) | 0.021 | Riesco- Eizaguirre et al, 200653 |
| American | 38/111 (34) | 18/98 (18) | 72 | 2.31 (1.21–4.41) | 0.012 | Kebebew et al, 200754 |
| Middle Eastern | 44/153 (29) | 25/143 (18) | 66 | 1.91 (1.09–3.32) | 0.027 | Abubaker et al, 200828 |
| Italian | 13/38 (28) | 6/64 (9) | 180 | 5.03 (1.72–14.73) | 0.003 | Elisei et al, 200830 |
| American | 15/40 (38) | 6/60 (10) | 24 | 5.40 (1.87–15.57) | 0.002 | Xing et al, 200955 |
| Overall | 174/611 (28) | 71/554 (13) | - | 2.71 (2.00–3.67) | < 0.001 | - |
| Predictive Probabilities | Positive: 28.5% | Negative: 87.2% | - | - | - | - |
The P values were calculated using Fisher’s exact test. The raw data were provided by Dr. Electron Kebebew and Dr. Khawla S. Al-Kuraya, through a personal communication, for references 54 and 28, respectively. The data from reference 55 included in this table has no overlap with the data in reference 51. This table is updated from reference 12.