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. Author manuscript; available in PMC: 2011 May 28.
Published in final edited form as: Cancer Lett. 2009 Nov 11;291(2):217–224. doi: 10.1016/j.canlet.2009.10.015

Fig. 5.

Fig. 5

NSC-127102 inhibits IL-8 and VCAM-1 gene expression. (A) HepG2 cells were treated for 24 h with 100 or 300 μM NSC-127102. Cells were also treated with 20 μM U0126 for 24 h. Cells were subsequently harvested and total RNA isolated. The effects of NSC-127102 on IL-8 and VCAM-1 mRNA levels were assessed by RT-PCR. Cyclophilin mRNA served as a loading control. (B) HepG2 cells were treated with 30 ng/ml TNF-α for 4 h to stimulate IL-8 gene expression in the presence or absence of 100 or 300 μM NSC-127102. Total RNA was isolated and IL-8 mRNA levels were assessed by RT-PCR.