Figure 3. Virtual synaptic activity selectively enhances threshold g_syn and I_M in B neurons.

A, time course of an experiment on a B neuron where the recording was switched between dynamic clamp and voltage clamp to measure the effects produced by the 40 s, 5 Hz stimulus template upon threshold g_syn (open diamonds) and I_M−30 (filled triangles). I–V plots (inset) measured before (1) and after (2) stimulation illustrate the increase in I_M−30 after leak subtraction. B, time constants for the recovery of threshold g_syn and I_M after 5 Hz stimulation were indistinguishable. C, time course of an experiment on a C neuron showing that activity elicited by the 40 s stimulus template under dynamic clamp had no effect on I_M−30 measured under voltage clamp. D, grouped data showing that virtual synaptic stimulation selectively increases I_M−30 in B neurons.