Table 2.
Relative mRNA abundance of GLYT1 and GSH-related enzymes in t-BOOH- and glycine-treated Caco-2 cells
Treatment |
||||
---|---|---|---|---|
Control | Glycine | t-BOOH | Glycine + t-BOOH | |
GLYT1 | 100 ± 6 | 75 ± 5.1 | 102.8 ± 13.4 | 77.5 ± 11.4 |
GCLC | 100 ± 1.9 | 105 ± 4.1 | 108.4 ± 2.9 | 103 ± 6 |
GCLM | 100 ± 3.4 | 102 ± 7.8 | 111.3 ± 8.9 | 120 ± 7.1 |
GS | 100 ± 5.3 | 122 ± 10.8 | 126.3 ± 10.2 | 108 ± 9.5 |
Values (expressed as percentage of control) are given as means ±s.e.m. n= 9–12 per group and are means of 3–4 experiments. In all cases P > 0.05 compared to control.