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. 2010 Feb 24;152(4):2130–2141. doi: 10.1104/pp.109.152728

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Figure 4. — Putative locations and functions of the genes in cluster 2₃₀₀. NAP1 may act as a Fe sensor, down-regulating the assembly of Fe-S clusters upon Fe deficiency. To counteract Fe shortage, Fe is released from ferritin and imported from the cytosol by IREG3. The expression of the ABC transporter TAP1, putatively involved in the export of Fe-S clusters, is up-regulated upon Fe deficiency, compensating for the reduced assembly. To prevent the accumulation of MgProto, the expression of HEMA1 and GUN5 is reduced. Green protein names indicate processes that are down-regulated upon Fe deficiency, and red arrows and protein names indicate up-regulation of the respective processes. [See online article for color version of this figure.]